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Propionyl Chloride | Premium Acylating Agent | CAS 79-03-8
Overview
Propionyl Chloride is a clear, colorless to pale yellow, highly volatile, and flammable liquid with a pungent, suffocating odor. In advanced organic synthesis, it is universally recognized as a premier acylating agent, utilized to introduce the propionyl group into alcohols and amines. Its exceptional reactivity makes it an indispensable building block in the global pharmaceutical, agrochemical, and specialty polymer industries.
Product Description
Propionyl Chloride | Premium Acylating Agent
Product Overview
Propionyl Chloride is a clear, colorless to pale yellow, highly volatile, and flammable liquid. In advanced organic synthesis, it is universally recognized as a premier acylating agent, utilized to introduce the propionyl group into alcohols and amines. Its exceptional reactivity makes it an indispensable building block in the global pharmaceutical, agrochemical, and specialty polymer industries.
At Shandong Yinglang Chemical Co., Ltd., established in 2016, we supply ultra-high-purity Propionyl Chloride (≥ 99.5%) specifically engineered for Contract Research Organizations (CROs) and industrial API manufacturers. Operating rigorously under Class 3 / 8 Dangerous Goods protocols, we ensure our product is packaged under strict, moisture-free Nitrogen blanketing to guarantee flawless reactivity upon arrival.
Technical Specifications (COA)
To ensure clean reaction profiles and high yields, trace moisture and free acid must be strictly minimized. Typical specifications:
| Purity | ≥ 99.5% |
|---|---|
| Propionic Acid | ≤ 0.3% |
| Free Chlorine / Phosgene | ≤ 0.05% |
| Boiling Point | 77 - 79°C |
| Density (at 20°C) | ~ 1.059 g/cm³ |
Key Applications
- Pharmaceutical Intermediates: The core acylating reagent utilized in the synthesis of numerous Active Pharmaceutical Ingredients (APIs) and specialized prodrugs.
- Agrochemical Synthesis: A critical building block for the large-scale production of high-performance systemic herbicides and pesticides.
- Polymerization Initiators: Reacted with peroxides to manufacture specialized peroxyesters, highly efficient radical initiators for plastics.
- Flavors & Fragrances: Used as an intermediate to synthesize specific propionate esters.
🔬 Superior Yields in Propionylation
When synthesizing complex APIs or agrochemicals, managing unwanted byproducts is critical. Our highly purified Propionyl Chloride minimizes free Propionic Acid (≤ 0.3%), ensuring that your acylation or esterification reactions proceed with maximum stoichiometric efficiency, reducing downstream purification costs and boosting your overall batch yield.
Strict Anti-Corrosive DG Packaging
Because Propionyl Chloride is highly flammable and reacts violently with ambient moisture, our packaging ensures absolute safety during ocean transit:
- 200 KG / 250 KG Heavy-duty UN-approved Steel Drums with specialized anti-corrosive inner linings, tightly sealed and purged with dry Nitrogen.
- ISO TANKS available for massive bulk liquid procurement.
⚠️ Safety & Transport Information (Class 3 / 8 DG)
- Transport Classification: Classified as Class 3 (Flammable) with Subsidiary Risk 8 (Corrosive).
- UN Number: UN 1815 | Packing Group: II
- Handling Precautions: EXTREME DANGER. Highly flammable. Reacts violently with water to form corrosive HCl gas. Causes severe burns. Operators MUST handle strictly inside a fume hood wearing full hazmat gear. Store in a cool, strictly dry, explosion-proof DG facility.
Request a Bulk Quote for Propionyl Chloride
Contact us today for the latest FOB/CIF pricing, detailed COA, and specialized Class 3/8 DG shipping estimates for your chemical facility.
Request a Quote Email Sales & Logistics Team
PACKING AND DELIVERY
Packing and delivery
We offer secure and compliant packaging for a wide range of chemical products, from laboratory bottles (100 mL, 250 mL, 500 mL) to customized bulk containers. All shipments follow international hazardous goods standards and include complete documentation such as COA and SDS. With reliable global logistics partners, we ensure safe, fast, and efficient delivery by air, sea, or land according to customer needs.
FAQ
Q1: What documents and certifications do you provide?
A Standard shipment includes COA (Certificate of Analysis) and MSDS (SDS). We also provide ISO 9001 certification and support third-party inspections like SGS or BV upon request.
Q2: Do you provide custom synthesis or formulation services?
A Yes. If you have specific purity requirements or a unique formulation, our R&D team can provide custom synthesis and adjust the stabilizers/inhibitors to meet your technical specifications.
Q3: What are your terms of payment?
A
For Orders ≤ $1,000: 100% in advance.
For Orders > $1,000: 30% T/T in advance, and the balance before shipment or against the copy of B/L. Irrevocable L/C at sight is also acceptable for bulk orders.
Q4: How long is your price valid?
A Chemical prices fluctuate due to the changes in raw material costs and exchange rates. Please contact our sales team for the latest real-time quotation.
Q5: What packaging and shipping ports are available?
A
We normally ship from Qingdao, Shanghai, or Ningbo.
Standard packaging includes 200kg Drums or 1000kg IBC Totes. We ensure strict safety compliance for both general and hazardous chemical cargoes.
Q6: It's my first time importing chemicals — can you help?
A Absolutely. Importing chemicals requires specific documentation. Our experienced logistics team will assist you with the entire process, including handling customs clearance documents and arranging the most suitable shipping method.