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5-Fluorocytosine | Premium Pharma API & Intermediate | CAS 2022-85-7
Overview
5-Fluorocytosine, widely known in the medical field as Flucytosine or 5-FC, is a white to off-white crystalline powder. As a highly specialized fluorinated pyrimidine analog, it possesses a dual identity in the global pharmaceutical industry. It serves directly as a potent antifungal Active Pharmaceutical Ingredient (API) for systemic infections. More strategically, it is the uncompromising foundational intermediate for synthesizing blockbuster anti-neoplastic (anti-cancer) drugs, such as Capecitabine, and critical anti-retroviral medications like Emtricitabine.
Product Description
5-Fluorocytosine, widely known as Flucytosine or 5-FC, is a white crystalline powder. As a highly specialized fluorinated pyrimidine analog, it possesses a dual identity in the global pharmaceutical industry. It serves directly as a potent antifungal Active Pharmaceutical Ingredient (API) for systemic infections. More strategically, it is the uncompromising foundational intermediate for synthesizing blockbuster anti-neoplastic (anti-cancer) drugs, such as Capecitabine, and critical anti-retroviral medications like Emtricitabine.
At Shandong Yinglang Chemical Co., Ltd., established in 2011, we supply bulk commercial volumes of Ultra-High Purity 5-Fluorocytosine to multinational pharmaceutical CDMOs and elite API formulators. Shipped globally as highly cost-effective Non-Dangerous Goods, our product is meticulously refined to eliminate trace heavy metals and related pyrimidine impurities, guaranteeing flawless regioselectivity for your most demanding synthetic pathways.
For complex oncology API synthesis and direct antifungal formulations, strict control of trace moisture and related isomeric impurities is absolute. Typical specifications:
| Purity (HPLC) | ≥ 99.5% |
|---|---|
| Moisture / Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Related Substances | ≤ 0.1% (Single Impurity) |
- Oncology API Synthesis (Capecitabine): The most strategically valuable application. Serves as the critical starting intermediate for synthesizing Capecitabine (Xeloda), a globally dominant oral chemotherapy medication for colorectal and breast cancers.
- Antiviral API Synthesis (Emtricitabine): Actively utilized as the precursor pyrimidine backbone in the synthesis of crucial HIV treatments and PrEP medications.
- Systemic Antifungal API: Formulated directly into Flucytosine capsules and IV solutions to treat severe Candida and Cryptococcus infections.
- Advanced Genomics Research: Used as a highly specific selection agent in fungal genetic engineering protocols.
When manufacturing sophisticated oncology APIs like Capecitabine, the purity of your fluorinated pyrimidine backbone dictates the safety and yield of the final drug. Unreacted starting materials or structurally similar pyrimidine impurities in your 5-Fluorocytosine feedstock can cascade through your multi-step synthesis, creating toxic byproducts that are incredibly difficult to separate. Yinglang Chemical guarantees an HPLC purity of ≥ 99.5%, rigorously capping single related impurities at ≤ 0.1%. This ensures absolute molecular precision and compliance for your CDMO operations.
As a highly stable pharmaceutical powder, we offer cost-effective and highly secure bulk packaging for global ocean transit:
- 25 KG UN-approved Fiber Drums with thick double-layered pharmaceutical-grade PE inner liners (Tightly sealed to ensure zero moisture ingress).
- 25 KG Heavy-duty cartons with PE inner liners.
- Palletized loads available for continuous, large-scale industrial API procurement.
Contact us today for the latest FOB/CIF pricing, detailed COA, and Non-DG logistics estimates for your pharmaceutical facility.
Request a Bulk Quote Email Tech & Logistics Team
PACKING AND DELIVERY
Packing and delivery
We offer secure and compliant packaging for a wide range of chemical products, from laboratory bottles (100 mL, 250 mL, 500 mL) to customized bulk containers. All shipments follow international hazardous goods standards and include complete documentation such as COA and SDS. With reliable global logistics partners, we ensure safe, fast, and efficient delivery by air, sea, or land according to customer needs.
FAQ
Q1: What documents and certifications do you provide?
A Standard shipment includes COA (Certificate of Analysis) and MSDS (SDS). We also provide ISO 9001 certification and support third-party inspections like SGS or BV upon request.
Q2: Do you provide custom synthesis or formulation services?
A Yes. If you have specific purity requirements or a unique formulation, our R&D team can provide custom synthesis and adjust the stabilizers/inhibitors to meet your technical specifications.
Q3: What are your terms of payment?
A
For Orders ≤ $1,000: 100% in advance.
For Orders > $1,000: 30% T/T in advance, and the balance before shipment or against the copy of B/L. Irrevocable L/C at sight is also acceptable for bulk orders.
Q4: How long is your price valid?
A Chemical prices fluctuate due to the changes in raw material costs and exchange rates. Please contact our sales team for the latest real-time quotation.
Q5: What packaging and shipping ports are available?
A
We normally ship from Qingdao, Shanghai, or Ningbo.
Standard packaging includes 200kg Drums or 1000kg IBC Totes. We ensure strict safety compliance for both general and hazardous chemical cargoes.
Q6: It's my first time importing chemicals — can you help?
A Absolutely. Importing chemicals requires specific documentation. Our experienced logistics team will assist you with the entire process, including handling customs clearance documents and arranging the most suitable shipping method.