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Anisole (Methoxybenzene) CAS 100-66-3

Overview

Anisole, widely recognized as Methoxybenzene, is a clear, colorless liquid with a pleasant, sweet, anise-like odor. As a highly stable and versatile aromatic ether, it acts as a critical building block in advanced organic synthesis. The electron-donating nature of its methoxy group makes the benzene ring highly reactive toward electrophilic aromatic substitution, unlocking pathways to manufacture vital pharmaceutical APIs, advanced agrochemicals, and premium synthetic fragrances.

Category

Product Description

Anisole (Methoxybenzene) | Pharma Intermediate
CAS: 100-66-3 High-Purity Synthesis Grade (≥ 99.5%) UN 2222 (Class 3 Flammable)
Product Overview

Anisole, widely recognized as Methoxybenzene, is a clear, colorless liquid with a pleasant, anise-like odor. As a highly stable and versatile aromatic ether, it acts as a critical building block in advanced organic synthesis. The electron-donating nature of its methoxy group makes the benzene ring highly reactive toward electrophilic aromatic substitution, unlocking pathways to manufacture vital pharmaceutical APIs, advanced agrochemicals, and premium synthetic fragrances.

At Shandong Yinglang Chemical Co., Ltd., established in 2011, we supply bulk commercial volumes of Ultra-High Purity Anisole to multinational pharmaceutical CROs and elite fragrance formulation houses. Operating securely under Class 3 Dangerous Goods protocols, our Anisole is packaged in tightly sealed, anti-static environments to ensure absolute molecular integrity and zero moisture ingress during global transit.

Technical Specifications (COA)

For sensitive API synthesis and high-end cosmetic formulations, strict control of trace moisture and phenol impurities is mandatory. Typical specifications:

Purity (Anisole) ≥ 99.5%
Moisture / Water ≤ 0.05%
Phenol Content ≤ 0.05%
Color (Pt-Co) ≤ 10
Density (at 20°C) 0.990 - 0.996 g/cm³
Key Applications
  • Pharmaceutical Intermediates: A foundational starting material used extensively in the synthesis of cardiovascular drugs and anti-inflammatory APIs (such as Naproxen).
  • Fragrances & Cosmetics: Formulated into luxury perfumes and soaps to provide a sweet-spicy aromatic profile and act as an effective solvent for other fragrance oils.
  • Specialty Solvent: Acts as an exceptionally stable, high-boiling solvent in advanced resin manufacturing and lithium-ion battery electrolyte formulations.
  • Agrochemicals: Utilized in the synthesis of high-efficiency crop protection chemicals.
🔬 Precision in Electrophilic Substitution

When synthesizing complex API backbones, the purity of your methoxybenzene starting material dictates the efficiency of downstream electrophilic aromatic substitution (such as Friedel-Crafts acylation or halogenation). Yinglang Chemical guarantees an Anisole purity of ≥ 99.5%, rigorously suppressing unreacted phenol and trace moisture. This ensures maximum regioselectivity in your para-directed substitutions, drastically reducing unwanted byproducts and maximizing your overall batch yields.

Secure Flammable DG Packaging

Because Anisole is a volatile and flammable liquid, we utilize highly secure, vapor-tight packaging for safe ocean transit:

  • 200 KG UN-approved Steel Drums, tightly sealed and Nitrogen-purged to prevent oxidation and moisture contamination.
  • ISO TANKS (20 MT) available for continuous, large-scale industrial procurement by pharmaceutical gigafactories.
⚠️ Safety & Transport Information (Class 3 DG)
  • Transport Classification: Classified as Class 3 (Flammable Liquid).
  • UN Number: UN 2222 | Packing Group: III
  • Handling Precautions: FLAMMABLE LIQUID AND VAPOR. Vapor accumulation can form explosive mixtures. Operators MUST handle strictly in well-ventilated, explosion-proof environments with proper grounding to prevent static discharge. Store in a cool DG facility.
Request a Bulk Quote for Anisole

Contact us today for the latest FOB/CIF pricing, detailed COA, and specialized Class 3 DG shipping estimates for your pharmaceutical or fragrance facility.

Request a Bulk Quote Email Sales & Logistics Team
Yinglang Chemicals' delivery
Yinglang Chemicals' delivery
Yinglang Chemicals' delivery

PACKING AND DELIVERY

Packing and delivery

We offer secure and compliant packaging for a wide range of chemical products, from laboratory bottles (100 mL, 250 mL, 500 mL) to customized bulk containers. All shipments follow international hazardous goods standards and include complete documentation such as COA and SDS. With reliable global logistics partners, we ensure safe, fast, and efficient delivery by air, sea, or land according to customer needs.

FAQ

Q1: What documents and certifications do you provide?

A Standard shipment includes COA (Certificate of Analysis) and MSDS (SDS). We also provide ISO 9001 certification and support third-party inspections like SGS or BV upon request.

Q2: Do you provide custom synthesis or formulation services?

A Yes. If you have specific purity requirements or a unique formulation, our R&D team can provide custom synthesis and adjust the stabilizers/inhibitors to meet your technical specifications.

Q3: What are your terms of payment?

A For Orders ≤ $1,000: 100% in advance.
For Orders > $1,000: 30% T/T in advance, and the balance before shipment or against the copy of B/L. Irrevocable L/C at sight is also acceptable for bulk orders.

Q4: How long is your price valid?

A Chemical prices fluctuate due to the changes in raw material costs and exchange rates. Please contact our sales team for the latest real-time quotation.

Q5: What packaging and shipping ports are available?

A We normally ship from Qingdao, Shanghai, or Ningbo.
Standard packaging includes 200kg Drums or 1000kg IBC Totes. We ensure strict safety compliance for both general and hazardous chemical cargoes.

Q6: It's my first time importing chemicals — can you help?

A Absolutely. Importing chemicals requires specific documentation. Our experienced logistics team will assist you with the entire process, including handling customs clearance documents and arranging the most suitable shipping method.

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