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CAS 507-09-5 Thioacetic acid
Overview
Thioacetic Acid (ethanethioic acid; CAS 507-09-5; C₂H₄OS, 76.12 g/mol) is a powerful thioacetylating reagent and convenient thiol surrogate. It installs SAc (thioacetate) groups on alcohol- or halide-derived substrates under mild conditions; the resulting thioacetates are readily hydrolyzed to thiols and further transformed to thioethers/sulfides—useful in pharmaceutical and agrochemical intermediates, sulfur-functional polymers, and late-stage sulfur incorporation with reduced odor versus free thiols. Supplied as a colorless to pale-yellow, strong-odor liquid, it is miscible with common organic solvents (e.g., MeOH/EtOH, THF, DCM, toluene) and has limited water solubility.
Product Description
CAS 507-09-5 Thioacetic acid
Thioacetic acid is a powerful thioacetylating reagent and convenient thiol surrogate that installs SAc groups under mild conditions and then releases R–SH cleanly by base- or hydrolysis-driven deprotection—useful for building thioethers/sulfides in pharma, agro, and polymer routes. It shows broad functional-group tolerance, enables low-odor sulfur introduction compared with free thiols, and works well in common organic solvents (MeOH/EtOH, THF, DCM, toluene).
Thioacetic Acid — Product Specification
CAS: 507-09-5 | Formula: C2H4OS | Molecular weight: 76.12 g/mol | Synonyms: Ethanethioic acid; S-acetyl donor
Identity & Form
| Product form | Colorless to pale-yellow liquid; strong characteristic odor |
|---|---|
| Solubility | Miscible with common organics (MeOH/EtOH, THF, DCM, toluene); limited solubility in water |
| Function | Thioacetylation of alcohol/halide-derived substrates; thiol surrogate for downstream thioether/sulfide synthesis |
| Documents | COA · TDS · SDS · DG documents |
Typical Specification (example)
| Assay (GC) | ≥ 98.0% |
|---|---|
| Acetic acid | ≤ 0.50% |
| Sulfur-containing impurities | ≤ 0.30% |
| Water (Karl Fischer) | ≤ 0.20% |
| Color (APHA) | ≤ 50 |
| Appearance | Clear, colorless to pale-yellow; free from visible particulates |
Applications & Handling
| Main uses | Introduce thioacetate (SAc) under mild conditions; deprotect to R–SH for thioether/sulfide formation in pharma, agro, and polymer routes |
|---|---|
| Handling | Corrosive; air-oxidation sensitive. Avoid strong oxidants and strong acids/bases (risk of H2S or thiol odor). Use appropriate PPE and ventilation per SDS. |
| Storage | Tightly closed, cool, dry; preferably under inert atmosphere; keep away from moisture/oxidants. |
Packaging & Logistics
| Packaging | 1 L / 5 L / 25 L amber bottles or drums; larger packs on request |
|---|---|
| Ports | Qingdao · Shanghai · Tianjin |
| To quote (please specify) | Purity grade, pack size, destination country/port, and required documents |
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Packing and delivery
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