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CAS 58-85-5 D-Biotin
Overview
D-Biotin (Vitamin B7 / Vitamin H; CAS 58-85-5; C₁₀H₁₆N₂O₃S, 244.31 g/mol) is a water-soluble vitamin and essential cofactor for carboxylases (ACC, PCC, PC, MCC) that support fatty-acid synthesis, gluconeogenesis, and amino-acid metabolism. Used across pharmaceuticals & nutraceuticals (tablets, capsules, softgels), food & beverages (fortification), animal nutrition (feed premixes for poultry/swine/aquaculture), cell-culture media, and diagnostics/bioconjugation (biotin–streptavidin systems).
Product Description
CAS 58-85-5 D- Biotin
D-Biotin (Vitamin B7, CAS 58-85-5): Water-soluble vitamin serving as an essential carboxylase cofactor (ACC, PCC, PC, MCC) supporting fatty-acid synthesis, gluconeogenesis, and amino-acid metabolism; used in pharma/nutraceutical tablets–capsules–softgels, food & beverage fortification, animal-feed premixes, cell-culture media, and biotin–streptavidin bioconjugation/diagnostics;
D-Biotin (Vitamin B7) — Product Specification
CAS: 58-85-5 | Formula: C10H16N2O3S | Molecular weight: 244.31 g/mol | Synonyms: Vitamin B7; Vitamin H
Identity & Form
| Appearance | White to off-white crystalline powder |
|---|---|
| Solubility | Sparingly soluble in water at RT; soluble in hot/alkaline water; soluble in DMSO/DMF; slightly soluble in ethanol; practically insoluble in non-polar solvents |
| Function | Water-soluble vitamin; essential cofactor for carboxylases (ACC, PCC, PC, MCC) |
| Documents | COA · TDS · SDS · Non-GMO/Allergen statements |
Typical Specification — Pharma/Nutra Grade (example)
| Assay (HPLC, dried basis) | 98.0 – 102.0% (w/w) |
|---|---|
| Identification | HPLC RT conforms; IR spectrum conforms |
| Specific rotation [α]D20 | +89° to +93° (c = 1, suitable solvent) |
| Water (Karl Fischer) | ≤ 0.5% (w/w) |
| Residue on ignition / Sulfated ash | ≤ 0.10% |
| Related substances (HPLC) | Individual ≤ 0.2%; total ≤ 0.5% |
| Heavy metals (as Pb) | ≤ 10 ppm (or per pharmacopeia) |
| Particle size (DC option) | D90 150–400 μm (direct-compression grade) |
| Microbial limits | TAMC ≤ 1.0 × 103 cfu/g; TYMC ≤ 1.0 × 102 cfu/g; E. coli/Salmonella: absent |
| Appearance | Free-flowing, no visible foreign matter |
Typical Specification — Feed/Premix Option (example)
| Biotin content | 1.0% · 2.0% · 10.0% on carrier (custom on request) |
|---|---|
| Carrier | Silica, CaCO3, or starch (as specified) |
| Moisture | ≤ 3.0% |
| Granulation | Free-flowing granules; low dust |
| Pelleting stability | Microencapsulated grades available |
Applications & Handling
| Main uses | Pharma/nutraceutical solid doses; food fortification; animal nutrition premixes; cell-culture media; diagnostics/bioconjugation |
|---|---|
| Handling | Stable when dry and protected from light; avoid strong oxidants; minimize heat/acid/alkali exposure |
| Storage | Tightly closed, cool, dry; protect from light and moisture |
Packaging & Logistics
| Packaging | 1 kg alu-foil bags (inner PE) · 5/10 kg bags · 25 kg fiber drum; premix packs on request |
|---|---|
| Compliance | USP / EP / FCC where applicable; Halal/Kosher upon request |
| Ports | Qingdao · Shanghai · Tianjin |
| To quote (please specify) | Grade (USP/EP/FCC or feed %), particle size/DC, pack size, destination, and required documents |
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PACKING AND DELIVERY
Packing and delivery
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