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CAS 594-19-4 Tert-Butyllithium Solution
Overview
Tert-Butyllithium (t-BuLi, CAS 594-19-4, C₄H₉Li) is a pyrophoric superbase supplied as 1.6–2.5 M solutions (hexanes/pentane/heptane). Uses: rapid deprotonation/DoM, lithium–halogen exchange, select anionic polymerizations. Lots are titration-verified with low moisture (COA/TDS). Handle strictly anhydrous under inert gas—ignites on contact with air/water. Custom concentrations and packaging available.
Product Description
CAS 594-19-4 Tert-Butyllithium liquid
Tert-Butyllithium (t-BuLi, CAS 594-19-4, C₄H₉Li) is a powerful, sterically hindered organolithium reagent widely used in fine chemicals, pharmaceuticals, polymer synthesis, and materials research. As a superbase and selective metalating agent, it drives rapid deprotonation, directed ortho-metalation (DoM), and lithium–halogen exchange, and can initiate living anionic polymerizations, enabling clean, high-yield route design and late-stage functionalization. Typically supplied as 1.6–2.5 M hydrocarbon solutions, its high basicity, reduced nucleophilicity, and fast kinetics deliver precise transformations when handled under strictly anhydrous, oxygen-free conditions.
Tert-Butyllithium (t-BuLi) — Product Specification
CAS: 594-19-4 | Formula: C₄H₉Li | Synonyms: tert-Butyl lithium; t-BuLi
| Product form | Hydrocarbon solution (colorless to pale-yellow) |
|---|---|
| Typical concentrations | 1.6–2.5 M (custom on request) |
| Solvent options | Hexanes · Pentane · Heptane (others on request) |
| Assay / Active base | Titration (reported on COA); concentration tolerance typically ±0.10 M |
| Moisture | Low-ppm by Karl Fischer (reported on COA) |
| Appearance control | Color (APHA) and clarity per COA |
| Stabilizers | None added |
| Key applications | Rapid deprotonation/metalationDirected ortho-metalation (DoM)Lithium–halogen exchangeInitiator for selected anionic polymerizations |
|---|---|
| Recommended conditions | Strictly anhydrous and oxygen-free systems; often run at low temperatures (e.g., to −78 °C) for selectivity and heat control |
| Safety | Pyrophoric & water-reactive. Handle under inert gas (N₂/Ar) by trained personnel with validated SOPs and dedicated quench procedures. |
| Documents | COA · TDS · SDS · DG documents |
| Lab packs | Septum-sealed glass bottles (e.g., 100 mL · 500 mL · 1 L) |
|---|---|
| Bulk | Inerted, sealed metal containers; flow-friendly concentrations available |
| Shipping | Dangerous Goods (pyrophoric/water-reactive); compliant packing & labeling |
| Ports | Qingdao · Shanghai · Tianjin |
| To quote (please specify) | Concentration (M), solvent, pack size, destination country/port, and required documents |
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PACKING AND DELIVERY
Packing and delivery
We offer secure and compliant packaging for a wide range of chemical products, from laboratory bottles (100 mL, 250 mL, 500 mL) to customized bulk containers. All shipments follow international hazardous goods standards and include complete documentation such as COA and SDS. With reliable global logistics partners, we ensure safe, fast, and efficient delivery by air, sea, or land according to customer needs.