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Oxalyl Chloride | Advanced Pharmaceutical Reagent | CAS 79-37-8
Overview
Oxalyl Chloride is a colorless to pale yellow, highly reactive, and fuming liquid with a penetrating odor. In the realm of advanced organic synthesis, it is universally recognized as the premium reagent for converting carboxylic acids to acid chlorides and is the critical driving component in the renowned Swern Oxidation. Its supreme advantage lies in its reaction profile: all its byproducts (CO, CO2, and HCl) are volatile gases, leaving behind an exceptionally clean reaction mixture that requires minimal downstream purification.
Product Description
Oxalyl Chloride | Pharmaceutical Grade Reagent
Product Overview
Oxalyl Chloride is a colorless to pale yellow, highly reactive, and fuming liquid. In the realm of advanced organic synthesis, it is universally recognized as the premium reagent for converting carboxylic acids to acid chlorides and is the critical driving component in the renowned Swern Oxidation. Its supreme advantage lies in its reaction profile: all its byproducts (CO, CO2, and HCl) are volatile gases, leaving behind an exceptionally clean reaction mixture.
At Shandong Yinglang Chemical Co., Ltd., established in 2016, we supply ultra-high-purity Oxalyl Chloride (≥ 99.5%) specifically engineered for Contract Research Organizations (CROs) and pharmaceutical API manufacturers. With our rigorous moisture exclusion protocols and UN-approved anti-corrosive packaging, we guarantee pristine reagent integrity upon arrival.
Technical Specifications (COA)
To ensure clean reaction profiles and high yields in API synthesis, trace moisture and residues are strictly minimized. Typical specifications:
| Purity | ≥ 99.5% |
|---|---|
| Appearance | Clear, colorless to pale yellow fuming liquid |
| Boiling Point | 63 - 64°C |
| Density (at 20°C) | ~ 1.478 g/cm³ |
| Residue on Evaporation | ≤ 0.05% |
Key Applications
- Swern Oxidation (Pharmaceuticals): The core reagent used to mildly and selectively convert primary and secondary alcohols into aldehydes and ketones, a critical step in complex drug synthesis.
- Acid Chloride Synthesis: Preferred over Thionyl Chloride for synthesizing acid chlorides, as it reacts under milder conditions and produces solely gaseous byproducts.
- Agrochemicals: Acts as a vital building block in the production of advanced herbicides and specialized crop protection chemicals.
🔬 The "Zero Residue" Advantage in API Synthesis
For pharmaceutical CROs, purifying complex molecular intermediates is costly and time-consuming. Oxalyl Chloride is heavily favored over traditional chlorinating agents because its byproducts—carbon monoxide, carbon dioxide, and hydrogen chloride—are all gases that simply bubble out of the reaction mixture. This leaves a clean, high-yield product that often requires no further distillation or chromatography.
Strict Anti-Corrosive DG Packaging
Because Oxalyl Chloride reacts violently with ambient moisture, our packaging ensures absolute safety during ocean transit:
- 250 KG Heavy-duty UN-approved Steel Drums with specialized anti-corrosive fluorinated inner linings, tightly sealed and purged with dry Nitrogen.
- Custom small-volume packaging (5 KG / 25 KG) available for university labs and pharmaceutical R&D centers.
⚠️ Safety & Transport Information (Class 8 / 6.1 DG)
- Transport Classification: Classified as Class 8 (Corrosive) with Subsidiary Risk 6.1 (Toxic).
- UN Number: UN 2927 | Packing Group: I/II
- Handling Precautions: EXTREME DANGER. Reacts violently with water to form toxic and corrosive gases. Toxic if inhaled. Operators MUST handle strictly inside a fume hood wearing full hazmat gear. Store in a cool, strictly dry DG facility.
Request a Technical Quote for Oxalyl Chloride
Contact us today for the latest FOB/CIF pricing, detailed COA, and specialized Class 8 DG shipping estimates for your pharmaceutical facility.
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PACKING AND DELIVERY
Packing and delivery
We offer secure and compliant packaging for a wide range of chemical products, from laboratory bottles (100 mL, 250 mL, 500 mL) to customized bulk containers. All shipments follow international hazardous goods standards and include complete documentation such as COA and SDS. With reliable global logistics partners, we ensure safe, fast, and efficient delivery by air, sea, or land according to customer needs.
FAQ
Q1: What documents and certifications do you provide?
A Standard shipment includes COA (Certificate of Analysis) and MSDS (SDS). We also provide ISO 9001 certification and support third-party inspections like SGS or BV upon request.
Q2: Do you provide custom synthesis or formulation services?
A Yes. If you have specific purity requirements or a unique formulation, our R&D team can provide custom synthesis and adjust the stabilizers/inhibitors to meet your technical specifications.
Q3: What are your terms of payment?
A
For Orders ≤ $1,000: 100% in advance.
For Orders > $1,000: 30% T/T in advance, and the balance before shipment or against the copy of B/L. Irrevocable L/C at sight is also acceptable for bulk orders.
Q4: How long is your price valid?
A Chemical prices fluctuate due to the changes in raw material costs and exchange rates. Please contact our sales team for the latest real-time quotation.
Q5: What packaging and shipping ports are available?
A
We normally ship from Qingdao, Shanghai, or Ningbo.
Standard packaging includes 200kg Drums or 1000kg IBC Totes. We ensure strict safety compliance for both general and hazardous chemical cargoes.
Q6: It's my first time importing chemicals — can you help?
A Absolutely. Importing chemicals requires specific documentation. Our experienced logistics team will assist you with the entire process, including handling customs clearance documents and arranging the most suitable shipping method.